Genetics for Smarter Medication Management
PGxOne™ Plus provides an additional tool for making informed drug management decisions with the goal of reducing adverse drug reactions and trial-and-error dosing and drug selection.
RGCC tests to discover, analyse and screen cancer cells in every step of the disease. The tests are designed to achieve: Detect potential early signs of undetected cancers, monitor existing diagnosed cancers, produce personalised guidance on which chemotherapy drugs and natural treatments could benefit individual patients.
https://www.rgcc-group.com/about-rgcc-tests
Nutrients for wound healing:
- Zinc: Essential for wound healing, immune function and tissue repair. Studies have shown that mild zinc deficiency could negatively affect T-cell function.
- Essential fatty acid deficiencies are associated with poor wound healing.
- Vitamin A helps to form scar tissue
- B1 (thiamine) deficiency can interfere with collagen synthesis
- B5 (pantothenic acid) accelerates the healing process.
- Vitamin C promotes the formation of collagen and elastin and deficiency can slow the healing process. Vitamin C supplementation has been shown to reduce the incidence of organ failure and time in the Intensive Care Unit in post surgically critically ill patients in a randomized prospective trial.
- Vitamin E aids in the healing of skin grafts.
- Bromelain an enzyme sourced from pineapple is strongly anti-inflammatory and helps decrease swelling following surgery.
- Serrapeptase is an enzyme which is able to dissolve and digest non-living tissue in the body while simultaneously reversing all forms of chronic inflammation. Supplementation is indicated after surgery with possible internal scarring.
Decrease pain following surgery:
- Homeopathic Arnica: Arnica has been traditionally used to help decrease pain, swelling and bruising following injury. A study looking at homeopathic arnica for pain management found it superior to placebo for patients recovering from tonsillectomy.
Constipation after chemotherapy:
- Magnesium citrate, dosage is dependent on individual. from 150mg up to 600mg. A good dosage indication is getting loose stool.
- Hydration, drink at least 8-10 glasses of clean water per day.
- Probiotics, high quality probiotic that contains lactobacillus acidophilus, lactobacillus planetarium and other friendly probiotics.
- Aloe vera juice, very soothing for the entire digestive tract, enhances bowel movement.
Diarrhoea after chemotherapy:
- L-glutamine helps to repair chemotherapy damaged intestines.
- Probiotics, which contains saccharomyces bollards and lactobacillus rhamnosus.
- Charcoal capsules, starting dose is 600mg 3x daily, increase up to 2400mg 3x daily.
Fatigue after chemotherapy:
- L-carnitine, an amino acid complex was identified to be deficient in 55% of cancer patients with fatigue. L-carnitine improved sleep, mood and decreased fatigue in a study of cancer patients with advanced cancer. (dosage around 3000mg/day)
- B Vitamins, an activated B complex with B1, B2, B3, B5, B6, B12 and folic acid
- CoQ10, is an anti-oxidant and essential for proper energy production. (100-200mg daily)
- Astralagus is one of the most important herbs in Chinese medicine. In addition to helping support the immune system it decreases fatigue. A 30% increased quality of life was reported from non-small cell lung cancer patients when given astralagus as compared to those receiving chemotherapy alone. Therapeutic dose is very high: 2grams x3 daily.
- Vitamin B12, iron and folic acid deficiency need to be checked and properly supplemented if deficient.
Hand Foot Syndrome PPE
PPE Palmar Planter Erythrodysthesia is the redness, peeling and desquamation of the hands and feet.
- Vitamin B6, women on (Xeloda) for advanced breast cancer had lower than expected reported rates of palmar planter erythrodysthesia when taking Vitamin B6 or using urea lotion. 300mg per day
- Topical DMSO lotion helps to alleviate symptoms. A strength of 99 percent 9prepared by compounding pharmacist) was used daily in study of doxorubicin induced PPE.
Nausea
- Ginger root (1 to 3grams of the dried root per day) is the best herb for nausea. The fresh grated root can be added to warm water and sipped throughout the day.
- MGN-3 (shitake mushroom complex fermented in rice bran oil), reduces many side effects of chemotherapy like nausea. 3-6grams daily
- AHCC- Active Hexose Correlated Compound 6grams reduces nausea and vomiting induced by chemotherapy.
Insomnia
- Magnesium supplement before bed helps to relax and aids to a restful sleep.
- Melatonin, the sleep hormone is very useful for sleeping problems. Starting dose is 3mg, can be build up to 20mg if needed.
- L-Theanine, a natural occurring amino acid, promotes relaxation and good sleep, improves mood, alleviates anxiety, stimulates the production of GABA. 100-400mg 30-60min. before bed time.
- Inositol is a nutrient of the B Vitamin family. Inositol helps to relieve stress and anxiety and boosts a sense of peaceful clarity. It is useful where anxiety is preventing sleep. 500mg-2g 1hour prior to sleep.
Neuropathy
- Vitamin B 6, diabetic neuropathy has long been treated with B vitamins, including B 6 but now research supports its use for chemotherapy- induced neuropathy as well. 300mg daily with food
- Benfotiamine, fat soluble thiamine (Vitamin B1) analogue, is highly efficient in alleviating neuropathic pain as well as other neuropathic symptoms. Useful to correct chemotherapy induced neurotoxicity.
- Alpha-lipoic acid, a potent antioxidant, significantly improved neuropathy at 600mg a day in a number of studies.
- Acetyl-l-carnitine has been shown to prevent nerve damage and reverse existing numbness, pain and tingling as well as sensation loss. Prevention and treatment is 500mg twice daily.
Mouth Inflammation and Ulceration
- Traumeel, a homeopathic complex remedy significantly reduced the severity and duration of chemotherapy-induced stomatitis (mouth inflammation and ulceration) in those undergoing bone marrow transplantation.
- Remedies within the complex include: Aconitum napellus, Arnica montana, Belladonna, Bellis perennis, Calendula officinalis, Chamomilla, Echinacea, Echinacea purpurea, Hamamelis virginiana, Hepar sulphuris calcareum, Hypericum perforatum, Mercurius solubilis, Millefolium, and Symphytum officinale.
- L-glutamine, helps to protect the mucosa and prevents mouth ulcers. 3-6grams daily
- Zinz and L-lysine are useful in healing mouth ulcers. Especially zinc spray or lozenges.
- Many herbs are available to heal mouth ulcers: myrrh tincture or oil, sage tincture or tea to gargle, aloe vera juice, goldenseal mouthwash.
Low White Blood Cell (Leukopenia and Neutropenia)
- AHCC (Active hexose Correlated Compound) is an alpha-glucan rich nutritional supplement produced from the mycelia of shiitake, 6grams/day
- MGN-3 (shitake mushroom complex fermented in rice bran oil), raises white blood cell counts and directly fights cancer cells. 3-6 grams/day
- Zinc is essential for increasing white blood cell levels. up to 80 mg daily can be essential
- Vitamin C up to 10 grams daily increases the production of white blood cells.
- Hyperthermia therapy increases white blood cell count.
Low Platelet Count ( Thrombocytopenia)
- Papaya leaf juice, successfully increased thrombocytes in a 2009 mice study. 20ml of juice every 2 hours until thrombocytopenia resolves.
- Herbs like goldenseal, ginseng and ashwaghanda are know to boost platelet levels.
- Vitamin D and Vitamin K 2 supplementation
- Shark oil (6000mg)
High Platelet Count
- Resveratrol has several effects on blood platelets including inhibition of platelet adhesion and aggregation, reduction in secretion of clotting factors from platelets, inhibition of cyclooxygenase, the proinflammatory enzyme involved in platelet activation and apoptosis of platelets. (250 – 500 mg daily
General radiation recommendations:
Many different vitamins, minerals, enzymes and herbs can counteract the side effects of radiation therapy and improve treatment. In general Vitamin A, C, E, D, Resveratrol, Coenzyme Q10 and a healthy diet with lots of broccoli, Brussel sprouts, cauliflower, kale, spinach will reduce the side effects of radiation.
- Green algae act as a chelating agent and protect against the harmful effect of radiation by binding with the radioactive elements and then excreting these from the body. Chlorella, Spirulina and “Modifilan”
- Astralagus: In Chinese hospitals Astragalus is now routinely used to help people recover from the negative effects of radiotherapy and chemotherapy. MD Anderson Cancer Center (Texas) researchers reported that cancer patients undergoing radiotherapy had twice the survival rates if they took astragalus during the treatment. In the West some herbalists routinely provide chemotherapy and radiotherapy patients with Astragalus, and apart from boosting the immune system (which of course both orthodox treatments damage) it also seems to stop the spread of malignant cancer cells to secondary healthy tissues.
- Curcumin increases effectiveness and decreases inflammation. 1500mg twice daily during treatment
- Niacin (Vitamin B3) improves the effectiveness of radiation treatment against thyroid tumours while at the same time reduces side effects. 3-6grams per day.
- Melatonin reduces oxidative damage from the production of free radicals. Several studies indicate that melatonin functions as a radioprotector, reducing the toxic effects of radiation on mammalian cells
- Essential Fatty Acids-Omega 3000mg – 4500mg
- Gingo biloba extract has a protective effect against cellular damage induced by irradiation due to its free-radical scavenging and antioxidant properties. 60mg twice daily.
- Selenium supplementation improved the general conditions of the patients, improved their quality of life and reduced the side effects of radiotherapy. At the dose of selenium used in several studies (200–500 μg/day), selenium
- Hyperbaric Oxygen Therapy can help minimise side effects and even restore healthy tissue by promoting healing. The Royal Marsden is currently undertaking clinical trials, although research has been reported in the USA. Whilst it seems advantageous to use it during radiation therapy, research also shows its benefits at a later stage too. supplementation did not reduce the effectiveness of radiotherapy, and no toxicities were reported.